P 371 Cytogenetic studies in retinitis pigmentosa patients

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P 371 Cytogenetic studies in retinitis pigmentosa patients

The retina contains due families of phspbolipnsc C (P, 6. and u). a reccctor-activated ewYmC that PFeratcs two iolraceUuhv s%xmd n&cngcrs, diacylgly&ol md I ,$5-inositol rrispbospbale. We hnvc charactaizcd the cDNA and par&d gene sh-ucnue for human PLCB4, a p isofurm which shares uighcsr sequence homology with dx norpA PLC from Drosophila. A muwion in tie nor@ PU: leads m I retinal demmtioo m d...

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Study of Patterns of Inheritance in Affected Patients with Retinitis Pigmentosa in Iranian Populations

Background and Aims: Retinitis pigmentosa (RP) is the most common form of inherited retinal degeneration, photoreceptors loss of which in the retina causes visual loss. The purpose of the present study was to determine patterns of inheritance in RP patients in Yazd to help the health professional for designing suitable laboratory testing for the high risk families. Materials and Methods: Thirt...

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Spatial judgments in patients with retinitis pigmentosa

Previous investigations into cortical plasticity in the presence of ocular disease have focused on central retinal damage. Perceptually, patients often report distortions of visual space which can be partially explained by perceptual filling-in. The mechanisms involved could also apply to peripheral field loss. Spatial interval discrimination was tested in 28 retinitis pigmentosa (RP) patients ...

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Symmetry discrimination in patients with retinitis pigmentosa

To investigate the relative sensory and perceptual contributions to central visual function of patients with retinitis pigmentosa (RP), we tested symmetry discrimination using block patterns with varying types of symmetric organization. Eleven control subjects with normal vision and 11 patients with RP with 20/30 visual acuity or better, viewed patterns presented for 255 msec. The patterns diff...

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Diagnostic imaging in patients with retinitis pigmentosa.

Retinitis pigmentosa (RP) is a progressive inherited retinal disease, and patients with RP have reduced visual function caused by a degeneration of the photoreceptors and retinal pigment epithelium (RPE). At the end stage of RP, the degeneration of the photoreceptors in the fovea reduces central vision, and RP is one of the main causes of acquired blindness in developed countries. Therefore, mo...

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ژورنال

عنوان ژورنال: Vision Research

سال: 1995

ISSN: 0042-6989

DOI: 10.1016/0042-6989(95)90631-2